2025 Week 2 NFL Betting Lines

Every Thursday or Friday, BetOnline.ag opens up lookahead lines for the following week. They are taken down on Sunday right before the games start.

Then they are re-opened once the games end.

Sometimes there can be a massive change based on injuries or poor play.

If there’s a big line movement from the lookahead lines, that will be notated.

NFL Week 2 spreads are subject to change. 

NFL Week 2 Lines

Thursday, September 11

• Washington Commanders at Green Bay Packers (-3)

Sunday, September 14

• New England Patriots at Miami Dolphins (-2½) 

• Jacksonville Jaguars at Cincinnati Bengals (-3½)
  • Lookahead line was -4½.

• Cleveland Browns at Baltimore Ravens (-12½) 

• New York Giants at Dallas Cowboys (-4)
  • Lookahead line was -3.

• Los Angeles Rams (-5) at Tennessee Titans

• Buffalo Bills (-7½) at New York Jets

• Chicago Bears at Detroit Lions (-4½)

• Seattle Seahawks at Pittsburgh Steelers (-2½)

• San Francisco 49ers (-7) at New Orleans Saints

• Carolina Panthers at Arizona Cardinals (-7)
  • Lookahead line was -4½.

• Denver Broncos (-3) at Indianapolis Colts

• Philadelphia (pk) at Kansas City (pk)
  • Lookahead line was KC -1½.

• Atlanta Falcons at Minnesota Vikings (-5½)
  • Lookahead line was -4½.

Monday, September 15

• Tampa Bay Buccaneers at Houston Texans (-1)
  • Lookahead line was -2½.

• Los Angeles Chargers (-3) at Las Vegas Raiders